Uterine Cancer

Definition

The most common gynecologic cancer, uterine cancer and it typically afflicts post, menopausal women between ages 50 and 60. It's uncommon between ages 30 and 40 and rare before age 30. Most premenopausal women who develop uterine cancer have a history of anovulatory menstrual cycles or other hormonal imbalances.

Causes of Uterine Cancer

Uterine cancer may be occur due to various predisposing factors:

• Prolonged estrogen therapy without use of progesterone.
• Low fertility index and anovulation
• History of uterine polyps or endometrial hyperplasia.
• History of infertility or failure of ovulation
• Familial tendency
• Abnormal uterine bleeding
• Obesity, hypertension, diabetes, or nulliparity

Uterine cancer is an adenocarcinoma that metastasizes late, usually from the endometrium to the cervix, ovaries, fallopian tubes, and other peritoneal structures. It may spread to distant organs, such as the lungs and brain, by way of the blood or the lymphatic system. Lymph node involvement can also occur. Less common uterine tumors include:

• Adenoacanthoma
• Endometrial stromal sarcoma
• Lymphosarcoma
• Mixed mesodermal tumors and leiomyosarcoma.

Complications of uterine cancer include:

• Intestinal obstruction
• As cites increasing pain
• Hemorrhage

Symptoms of Uterine Cancer

If you have this disease, then various symptoms are associated with it. The patient history may reflect one or more predisposing factors. In the younger patient, it may also include:

• Reveal spotting and protracted
• Heavy menstrualperiods.

Treatment of Uterine Cancer

If you have this disease, then you should be use Possible treatment such as:

• For the treatment of this disease you can use surgery, it usually involves total abdominal hysterectomy, bilateral salpingo-oophorectomy or, possibly, omentectomy with or without pelvic or paraaortic lymphadenectomy. Total pelvic exenteration removes all pelvic organs, such as the rectum, bladder, and vagina, and is only performed when the disease is sufficiently contained to allow surgical removal of diseased parts.
• You should Provide supportive care for adverse effects of radiation therapy or chemotherapy.
• Another treatment for this disease is Radiation therapy. It is used when the tumor isn't well-differentiated, intracavitary radiation, external radiation, or both may be given 6 weeks before surgery to inhibit recurrence and lengthen survival time.
• To minimize skin breakdown and reduce the risk of skin infection, you should tell the patient to keep the treatment area dry, and avoid wearing clothes that rub against the area, and avoid using heating pads, alcohol rubs, or irritating skin creams. Because radiation therapy increases susceptibility to infection, encourage her to avoid people with colds or other infections.
• You can also use Hormonal therapy, using antiestrogenies such as tamoxifen, shows a response rate of 20% to 40%.
• Other treatment include Chemotherapy such as cisplatin and doxorubicin. It is usually attempted when other treatments have failed.