Squamous Cell Carcinoma

Definition

Squamous cell carcinoma is an invasive tumor and it may be occur from keratinizing epidermal cells and has a high metastatic potential to distant parts of the body. It's the second most common skin cancer and third most common cancer in men and the fourth most common cancer in women. Mostly it occurs in fair-skinned white males over age 60. Patients with fair skin and a history of sun exposure are at increases risk for SCC, as well as other forms of skin cancer.

Causes of Squamous cell carcinoma

Various factors that may cause Squamous cell carcinoma. Predisposing factors that are associated with include:

• Overexposure to the sun's ultraviolet rays
• The presence of premalignant lesions
• X-ray therapy
• Ingestion of herbicides containing arsenic
• Chronic skin irritation and inflammation
• Exposure to local carcinogens such as tar and oil
• Hereditary diseases such as xeroderma pigmentosum and albinism

Other factors that contribute to this disease such as Smoking, it has recently been linked to skin cancer and may increase the risk of developing skin cancer threefold, independent of age, gender, sun exposure, and other predisposing factors that are listed above.

Symptoms of Squamous cell carcinoma

If you have this disease, then various symptoms of this disease include:

• Mostly SCC begins in the upper part of the epidermis
• Develops on sun-exposed areas of the body such as the face, ears, dorsa of -the hands and forearms.

Transformation from a premalignant lesion to see may begin with induration and inflammation of the preexisting lesion. When see arises from normal skin, the nodule grows slowly on a firm, indurated base. If untreated, then this nodule eventually ulcerates and invades underlying tissues. Metastasis can occur to the regional lymphnodes, producing characteristic systemic symptoms of pain, malaise, fatigue, weakness, and anorexia.

Treatment of Squamous cell carcinoma

If you have this disease, then you should be use Possible treatment such as:

• All major treatment methods have excellent cure rates. Depending on the lesion, treatment may consist of such as wide surgical excision, electrodesiccation and curettage, cryosurgery.
• Another treatment for this disease is Mohs surgery, it has the highest cure rate for tumors greater than 2 em, recurring tumors, or certain cancers found along the nerves under the skin, face, or genital areas.
• You can also use radiation therapy, it generally for older or debilitated patients and for those areas where surgery is difficult, such as the eyes, ears, nose, and throat.
• Treatment for this disease is lymph node, you can use it for removal for very large and deeply invasive tumors.
• Another treatment is chemosurgery, it is reserved for resistant or recurrent lesions.
• You should apply the sunscreen at least a half hour before exposure and re-apply frequently. You should be use a sunscreen throughout the year, even for winter sun exposure.